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A thorough understanding of the vital metabolic processes and pathways that enable malaria parasite's complex biology is significantly hindered due to the lack of functional characterization of its genome.
For example, the same currents and pathways that enable larval recruitment can expose an ecosystem to invasive species, pathogens, parasites, and pollutants, which can undermine the resilience of a system (McClanahan and others 2002).
Here we present a novel method, which we term Adaptation of Metabolism (AdaM), to identify reactions and pathways that enable system adaptation upon external perturbation.
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Overexpression of αv integrins activates and modulates signalling pathways that enable tumour cells to switch to an invasive phenotype (Seftor et al, 1999).
Towards the goal of valorizing the hemicellulose fraction of lignocellulose, we designed and validated a set of pathways that enable efficient utilization of pentoses for the biosynthesis of notable two-carbon products.
However, tumor cells have a remarkable ability to adapt to such treatments through functional redundancies and activation of compensatory signaling pathways that enable them to tolerate the presence of targeted drugs.
Doing so will translate into lower drug production costs and shed light on the intermediary pathways that enable high protein expression.
O. carboxidovorans, N. hamburgensis, and B. japonicum each have unique genetic pathways that enable them to have specialized functions such as CO oxidation, nitrite oxidation, and N2 fixation.
In vivo, this acid-base balance is regulated through various pathways that enable the production and transportation of hydrogen ions so that intra- and extracellular pH are physiologically controlled (Gillies et al., 2004).
In recent years, it has become clear that plant defense responses are complex, and that they arise from crosstalk between different hormonal signaling pathways that enable specificity of responses to different pathogens and fine-tuning of defense responses [ 5, 9].
DOI: http://dx.doi.org/10.7554/eLife.08931.001 Cells have communication systems called signaling pathways that enable them to detect and respond to changes in their surrounding environment.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com