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Anti-DNA antibodies are the serological hallmark of systemic lupus erythematosus, and participate in the pathogenesis of lupus nephritis by cross-reacting with multiple renal antigens.
Both experimental and clinical studies have shown that oxygen-derived free radicals rise in the plasma after thermal injury and participate in the pathogenesis of tissue damage.
Astrocytes and microglial cells did not show positive TUNEL staining after infection with Itacaiunas or Curionopolis virus, indicating that these cells are activated and participate in the pathogenesis of the CNS rather than succumb to it.
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Members of the claudin gene family have been demonstrated to be aberrantly regulated, and to participate in the pathogenesis of various human cancers.
Recently, CxHCs have been associated to denervation-induced skeletal muscle atrophy (1), and may also participate in the pathogenesis of corticoids induced muscle atrophy.
In conclusion, these cases indicate that hematopoietic stem cells and T-cells participate in the pathogenesis of psoriasis.
Human RA FLS are major producers of IL-6 and IL-8 in synovium and these proinflammatory cytokines participate in the pathogenesis of RA.
Substantial laboratory and epidemiologic evidence shows that influenza A and bacterial pathogens often participate in the pathogenesis of pneumonia.
Many type 1 cytokines exhibit vasoactive properties and are likely to participate in the pathogenesis of vascular leak.
More recently, it has been shown that cells of the innate immune system, including NK cells [6], [7] and macrophages [8] participate in the pathogenesis of CAV.
Our data suggest that proinflammatory Th1 and Th17 responses may participate in the pathogenesis of MCD.
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CEO of Professional Science Editing for Scientists @ prosciediting.com