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These findings indicate that injecting germ cells directly into adult testis facilitates and enable fast generation of donor spermatogenesis and offspring compared to previously described methods.
Triglycerides were lower for Long Life Family Study probands and offspring compared to both FHS cohorts.
Diabetes, chronic pulmonary disease and peripheral artery disease tended to be less common in LLFS probands and offspring compared to similar aged persons in the other cohorts.
Evidence for the relationship between hyperglycaemia and adverse effects is stronger when studied between mothers and offspring (compared with fathers and offspring).
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Maternal undernutrition resulted in a significant reduction in birth weight of UNP and UNPL offspring compared to Control and birth weight of UNL offspring was similar to that of Controls (Table 2).
The aim was to study cardiovascular and metabolic risk factors 11 years after the delivery among women who were diagnosed with mild, moderate, or severe preeclampsia, and their offspring, compared with women without preeclampsia and their offspring.
A study of DNA methylation in centenarians and their offspring compared with the offspring of non-long-lived individuals and young individuals showed that the offspring of the centenarians delay age-related methylation changes (Gentilini 2012).
Post-hoc analysis demonstrated a significant increase in ovarian hyperoxidised Prx 3 in UNP, UNPL and UNL offspring compared to Controls (Figure 9B).
We further used signalling intensities of individual probesets on each microarray to correlate global expression levels between parents and their own offspring, compared to offspring of other birds, and found a significantly higher correlation within families than between (mean difference in correlation coefficients 0.0017 ± 0.0002 (SEM), t = 8.2, P < 0.001).
A post-weaning HF diet significantly increased ovarian hyperoxidised Prx 3 in Control offspring (Cont-HF; p<0.001) and although levels were higher in UNP-HF and UNPL-HF offspring compared to Cont-HF offspring, these were not different from their respective chow fed counterparts.
They reproduce late in life and have few offspring compared to other fish.
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