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Since variability of the BoNT gene and protein sequence within botulinum neurotoxin subtypes A has been reported and these sequence variations impact on antibody binding and neutralisation [21], the capacity of mouse and chimeric antibodies to neutralise BoNT/A2 and /A3 was evaluated using a mouse neutralisation assay with 5 estimated MLD50 per mouse of each toxin subtype.
Either way, to conceive of the government of Hong Kong as being an exercise in the identification and neutralisation of dissidents or all those deemed to be "unpatriotic" would be profoundly counterproductive.
Energy escalation related to combustion, solution, and neutralisation has been presented, along with pyrophoric scenarios.
An overview of the design is presented giving the basic information on beam transmission and neutralisation, gas flow and pumping.
An imposed boundary condition for the beam injection allows beam front and neutralisation effects to be described suitably.
Radiosynthesis and formulation is rapid (<2 min), proceeds at ambient temperature and simply requires addition of 68Ga3+ solution to the conjugate and neutralisation with acetate solution.
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IIH participated in the design of the study, coordinated animal experiments and virus neutralisation assays and helped drafting and revising the manuscript.
sgp130 was given 30 min prior to the start of laser treatment and 3 h after ending PDT treatment, at a time point when we expected an increase of local IL-6 and sIL-6R α and its neutralisation to be optimal.
The level of Cyr61 in Du145 cells was fairly moderate among the four PCa cell lines; therefore, we explored the function of Cyr61 in Du145 cells by siRNA and antibody neutralisation, as well as forced expression and protein treatment, whereas overexpression and r-hCyr61 protein stimulation were employed in the study on LnCap cells.
Thus, the organic material is characteristic for wetlands, but hardly usable as substrate for microbes and may retard sulfate reduction and pH neutralisation of re-submerged sulfuric material.
Furthermore, it also showed that 5% serum of SSc patients promoted the expressions of collagen 1, collagen 3 and α-SMA of DVSMCs, and the neutralisation of IL-17A in the culture medium suppressed the expressions of these proteins.
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