Sentence examples for and modulation of this from inspiring English sources
This review highlights the importance of Cav1.2 channel overexpression, the accumulation of hyperphosphorylated tau and suppression of autophagy in Alzheimer's disease and modulation of this pathway by isradipine.
Numerous studies have implicated Shh signaling in medulloblastoma pathogenesis, and modulation of this pathway has led to the vast majority of mouse models of medulloblastoma currently available.
CR cells in layer 1 may actively trigger the induction, maintenance and modulation of this Ca2+ spikes by their long-range horizontal axons, the high density of output synapses and their network activity.
The RhoA/Rhokinase pathway has now been proposed as a new target for the treatment of AHR in asthma [ 37, 38] and modulation of this pathway by miR-133a might provide a new insight into the treatment of AHR [ 17].
In summary, Noxa and its antagonist Mcl-1 are part of an important component of the mechanisms to re-establish RBC numbers upon blood loss and modulation of this pathway could be envisaged in therapeutic options for treatment of anemia.
Our data corroborate previous studies demonstrating that NFAT activation is a key component of the angiogenic response induced by VEGF in endothelial cells [ 22], and modulation of this pathway may represent an adverse effect of calcineurin inhibition during transplant immunosuppression.
It is therefore likely that PDI plays a role in viral replication, translation, or encapsidation, and modulation of the expression of this protein would interfere with viral replication.
Further exploration and modulation of the stress response in this hRPE model may provide new targets for the development of novel therapeutics to slow the development of drusen as well as the advancement of dry AMD.
The rhythm and modulation of the abbot's talk were remarkable.
T. arundinaceum has been used as a model to study the beneficial effect of trichothecenes on the Trichoderma biocontrol activity and modulation of plant defense responses of this fungus (Malmierca et al. 2012).
The main outcome was that skin temperature does not affect the selection and modulation of exercise intensity in this type of short-duration exercise.
