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Given the requirements for new antimalarials with novel modes of action, we propose that fatty acid metabolism, which appears to achieve a stage-specific balance between salvage from the host and modification by the parasite, represents an attractive process with significant therapeutic value.
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Owing to the unique hierarchical structure and modification by butyl alcohol, the electrochemical stability and the charge/mass transport of the Co Al-LDHs was improved.
Expansion of this 'toolbox' will result from extending the search into lipid A biosynthesis and modification by bacteria living at the extremes.
Thirdly, the refinement and modification by adapted Snake are beneficial for further precision upgrade.
To our knowledge, this is the first large-scale study (covering the eastern United States) to investigate the association between long-term exposure to PM2.5 and mortality rate and effect modification by the chemical constituents of PM2.5.
Also, the influence of these hormones on outcome and their modification by the chronology of lesion and therapeutic maneuvers are considered.
Fig. 4 Determination of kraft lignin pHpzc before and after modification by the drift method.
The proteins identified in this study are target candidates for alkylation and functional modification by the phospholipid aldehyde POVPC.
These proteins then undergo meticulous folding by molecular chaperones, correct disulfide bond formation by protein disulfide isomerases, and proper oligosaccharide modification by the oligosaccharyltransferase complex, sugar trimming enzymes, and calnexin/calreticulin cycle in the ER [1], [2].
Disease activity was recorded by the SLE disease activity index 2000 (SLEDAI-2 K), both with and without index modification by the exclusion of laboratory items for hypocomplementemia and anti-dsDNA antibody binding [ 31].
During the oxidation reaction with H2O2, organic ligands dissolve into the solvent [28], and the surface modification by the amine functional group prevents the quantum dots from agglomeration [29].
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