It was a safe, quiet place, in an area far from where the women had lived and might be recognized.
When these modified self proteins are inefficiently cleared, they may be presented to the immune system and might be recognized as 'nonself' [ 51].
Perhaps when one member of the complex is defective or missing, surfaces on other members of the complex are abnormally exposed and might be recognized as 'misfolded', thus triggering the UPR.
"Now you can say them, but you can't say 'girl.' " Mr. Lehrer is not a recluse, though he resists all publicity unless he has something to sell, refuses television interviews (because he'd be asked to perform and then might be recognized in airports) and acknowledges having encouraged rumors that he was dead, in the vain hope of cutting down on his junk mail.
Furthermore, it has been shown that these mutations possibly result in changed peptides that are presented by major histocompatibility complex II and thus might be recognized as non-self by the immune system.
The biggest lesson so far, some say, is that despite years of discussing and imagining how a bioterrorism attack might occur, and how it might be recognized, the actual attack took everyone by surprise.
With a better understanding of the astrocyte roles in both brain physiology and pathology, gliotransmission might be recognized as a target for developing new anti-epileptic therapies.
With a better understanding of astrocyte roles in both brain physiology and pathology, gliotransmission might be recognized as a target for developing new anti-epileptic therapies.
We recently developed a set of quality indicators for headache care, intended to be applicable across countries, cultures and settings so that deficiencies in headache care worldwide might be recognized and rectified.
One or more RDR(s) producing PLMVd-dsRNAs are thus presumably involved, which could be activated by the peculiar structural features of the genomic viroid RNAs, circular and linear strands without cap structure and poly-A tail that might be recognized as aberrant RNAs [54], [55]; actually, some hotspots are in a 21-nt phase with the hammerhead-mediated self-cleavage sites in both polarities.
End labeling with a fluorescent tag offers an attractive alternative; however, these tags are generally big chemical moieties, and once attached to the DNA substrate might be recognized as 'DNA damage' and interfere with the target repair reaction.
