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This is an unexpected finding that might be biased by inconsistent definitions and methods of ascertaining smoking history, which were not standardized in the clinical datasets.
It is difficult to directly compare the rate of emergencies we observed to other studies given different sampling strategies, populations, time periods under study, and methods of ascertaining CRC emergencies.
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These related to the consent model and the methods of ascertaining, contacting and interviewing participants with breast cancer.
Studies are needed to validate different and feasible methods of ascertaining gestational age compared to accurate gestational age dating (early ultrasonography) in LMIC.
Several methods of ascertaining and classifying childhood neoplasms for epidemiological study have been evaluated using material from the University of Manchester Children's Tumour Registry (CTR), which includes data from several sources on children with neoplasms first seen in the period 1954-73 werewere under 15 years old and living in the Manchester Regional Hospital Board area at the time.
We carefully addressed missingness with multiple methods of ascertaining exposures, and addressed inconsistencies in data recording by removal of clinically illogical extreme outliers.
On the basis of the survey of the methods literature and our group's experience with methods of ascertaining MIDs, 3 4 17–22 we will develop initial criteria for evaluating the credibility of anchor-based MID determinations.
Although EDC proponents frequently claim that clinical trial data quality improves with use of such systems, studies supporting this contention have yet to appear in the peer-reviewed literature, and it is not clear whether traditional methods of ascertaining data quality suffice for EDC trials.
Further studies are needed to better understand the factors contributing to these differences, such as sensitivities of the assays, use of very short DNA fragments in MPRAs, methods of ascertaining the predictions, and effects of sample sizes.
However, there was significant heterogeneity between studies which may be due to differences in lengths of follow-up, methods of ascertaining the presence of ulcers and the use of different cut-off points (thresholds) for some of the tests [ 6].
TLFB28 is an established valid and reliable method of ascertaining alcohol consumption in adolescent populations over a reference period ranging from 7 to 365 days [ 35].
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