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Given a mean heteroplasmy and an organismal age, the parameterised BDP model predicts the structure of the heteroplasmy distribution (see 'Materials and methods' and next section).
Moreover, our RNA-Seq analyses (see Materials and Methods and next sections), confirmed that 50 (79%) of the retrocopies are expressed and, as expected for functional retrocopies (Kaessmann et al. 2009), most (96%) are expressed in the testis, including 14 candidates that exhibited tissue-specific expression (supplementary table S5, Supplementary Material online).
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It should be considered that animals undergoing cytokine mRNA and protein analysis before induction of AIA (day 0) were under the influence of systemic immunization with mBSA (see Materials and methods and the next paragraph for details).
An amateur mathematician, Rice developed her own notation and method and over the next few years discovered another four types of pentagon that tile the plane.
The causative virus was fully characterized by using conventional methods and next-generation sequencing.
Using a simple model of modular rearrangement (for details, see Materials and Methods), we next explored the mechanisms that can facilitate the formation of novel arrangements.
"Both bring the tools and methods to facilitate our next phase of growth".
To eliminate the noise from a list which might otherwise place pharmaceutical formulations and cryptography methods next to skateboard components, we combined the researchers' algorithm with a list of about 250 historically important patents compiled by their team.
For practical purposes, a more useful comparison would be that between a clone library sequencing method and a next-generation sequencing method on the same organism.
Subsequently, we apply our method to both synthetic and next generation sequencing data from various species.
Besides epidemiological and conventional microbiological methods, the next-generation gene sequencing technology permits prompt detection of genomic and transcriptomic profiles associated with invasive phenotypes.
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