To facilitate uncertainty analysis applications a comprehensive approach and methodology must be developed and applied, in contrast to the historical approach where sensitivity analysis were performed and uncertainties then determined by a simplified statistical combination of a few important input parameters.
Despite the informal nature of these tests, study design and methodology must be given careful consideration if they are to yield sound data.
As with any human study, assumptions in experimental design and methodology must be considered when interpreting our results.
For the Møller and Cuervo analysis to work, variation due to operator and methodology must be small relative to the actual variation in mutation rate between species.
Since these structures are subjected to varying environmental and operational conditions, reliable SHM methodologies must be capable of not misattributing to damage changes due to environmental conditions.
Finally, we show that the variability in the energy consumption is improved by using OBB and suggests that new sizing methodologies must be studied to fully benefit from the wide back plane voltage range available in UTBB FD SOI technology for the design of robust energy efficient digital circuits.
Due to ever increasing regulatory driving forces, more stringent and usually more expensive treatment methodologies must be used to achieve lower metal releases to the environment.
Newer tests developed in research settings might provide more incisive indicators of immune status that could help identify exposure, susceptibility, or preclinical disease states, but their methodologies must be refined and tested in multicenter studies before they can be used reliably in public health applications.
Such a move poses at least two major challenges to identification of relevant evidence: first, search methodologies must be sufficiently robust and rigorous to preserve the credibility of the review, and, second, iterative and intuitive search procedures may render it problematic "to use completely reproducible and transparent search and selection strategies" [ 9].
