The phrase "and maximal dose of" is correct and usable in written English.
It can be used in contexts related to medicine, pharmacology, or dosage recommendations.
Example: "The patient was prescribed a medication with a recommended starting dose of 10 mg and maximal dose of 40 mg."
Alternatives: "and highest dose of" or "and peak dose of".
After adjustment on IGS2, inappropriate initial antibiotic therapy and maximal dose of vasopressors remained independent prognostic factors, whereas V max E′ became quite not significantly associated with ICU death (p = 0.07).
After adjusting for the SAPS II score, inappropriate antibiotic therapy and maximal dose of vasopressors were the sole factors independently associated with ICU mortality, while a trend was only observed for lateral E′ maximal velocity.
After adjusting for the SAPS II score, inappropriate initial antibiotic therapy and maximal dose of vasopressors remained independent factors for ICU mortality, whereas a trend was only observed for lateral E′ maximal velocity (OR 1.11 [CI 95%% 0.99 1.23]: p = 0.07).
After adjusting for the SAPS II score, the initial inappropriate antibiotic therapy and the maximal dose of vasopressors remained independent factors related to ICU mortality.
Hemodynamical and respiratory parameters and associated treatments were collected at the introduction and at the maximal dose of norepinephrine.
Left ventricular diastolic function assessed using lateral E′ maximal velocity was independently associated with ICU death in conjunction with inappropriate initial antibiotic therapy, maximal dose of vasopressors and SOFA score.
The efficacy was also confirmed in patients at maximal dose of metoprolol and in patients with recurrent angina [ 15].
To study the effects of insulin on TBC1D1 Ser phosphorylation, anaesthetized mice were injected with saline or a maximal dose of insulin, and tibialis anterior muscles were dissected 10 min later.
End points of the test were an achievement of the target heart rate (85% of the maximal heart rate predicted for age), the maximal dose of dobutamine and atropine, >2 mV downsloping ST-segment depression measured 80 ms from the J point compared with baseline, hypertension (blood pressure >240/120 mmHg), a decrease in systolic blood pressure of >40 mmHg, and significant arrhythmias.
LV diastolic function assessed by the measurement of lateral E′ maximal velocity was independently associated with ICU mortality, in conjunction with the inappropriateness of the initial antibiotic therapy, the maximal dose of vasopressors administered and the SOFA score.
It follows that definitive evidence supporting maximal lowering of LDL-C or maximal dose of statins is still lacking and guidelines, if they are to be evidence-based, should acknowledge this uncertainty.
