Thus, (Ca+2 ER depletion-mediated oligomerization of BiP stands to contribute to UPR activation by increasing the burden of free unfolded proteins and by lowering the availability of monomeric BiP to repress the stress transducers.
Alternatively, the apparent decline in intracellular Aβ signal may be the result of the intense reactivity of extracellular Aβ, potentially sequestering antibodies and creating steric hindrance, thus lowering the availability of intracellular epitopes.
"Widespread expectations that the economy will continue to recover gradually in the quarters ahead, that interest rates will remain low, and the ongoing impact of policy measures aimed at supporting the availability and lowering the cost of credit all provide reasons for optimism that activity will continue to gain momentum in the quarters ahead," he said.
It can be argued that modifying external factors such as increasing the availability and lowering the cost of healthy foods in the cafeteria might promote the consumption of fruits and vegetables among the nurses [ 35].
We anticipate that advancing technology will aid in both increasing the availability and lowering the costs of using such models and enable us to further explore this question in the future.
These interventions could include behaviour change, communication about the risks of indoor air pollution, construction of improved cooking implements or increasing availability and lowering the cost of alternative cooking methods and/or cleaner fuels, one example being the solar-powered cookers utilized in Kenya, Zimbabwe, and Nepal, among other countries [ 32].
This study shows that the mild digestion agents used dissolve an unexpectedly high proportion of rare metals present in the byproducts and that increasing the heat and residence time lowers the availability of the metals.
For example, a well-balanced diet, combined with exercise, may lower the availability of these resources for CMV, and could help control its replication.
By doing so, it lowers the availability of carbonate ions, which oysters and other shellfish use to build their shells.
Major efforts are being made by the Global Fund and other organisations to increase the availability and lower the cost of antimalarials.
