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In AS and spondyloarthritis (SpA) a number of recent studies have defined transcriptional profiles generated from peripheral blood mononuclear cells (PBMCs) isolation requiring immediate sample processing, which is not suitable for larger multicentre studies and limits the viability of such an approach [ 7].
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Moreover, an additional drawback is their limited shelf life, which limits the viability of ready-to-use antibody-based sensors [ 2].
The cytotoxicity tests proved that glycinated KL lignin limits the viability of cells only slightly, and the final hyaluronan/lignin hydrogels were non-toxic materials.
One reason is that P-glycoprotein (Pgp) efflux pumps are usually overexpressed and lead to drug efflux in the cancer cells, which limits the viability of many chemotherapeutics.
Together, these results indicate that GTPases can limit the viability of BCG and influence its vascular response.
While Ms. Yu has succeeded tiptoeing along such self-imposed limits, these kinds of inhibitions, China scholars say, are likely to limit the viability of Internet businesses -- particularly those that traffic in information or anything politically sensitive.
The possibility that oxidants may limit the viability of biological habitats is particularly timely in the light of recent suggestions of contemporary flowing water on Mars.
Public intervention in high-tech sectors is often advocated to resolve market imperfections that may possibly limit the viability of young high-tech enterprises.
This limited the viability of the imaging preparation to a few hours, corresponding to a single behavioral session.
As a result of this reduction limited the viability possible to achieve post-concentration, as the final viabilities were below the target by 15 20%.
The roles of demographic, genetic mechanisms and their interactions in limiting the viabilities of species or populations have stirred much debate and remain difficult to evaluate in the absence of demography-genetics conceptual and technical framework.
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CEO of Professional Science Editing for Scientists @ prosciediting.com