Of note, dosing mismatch was the only area in clinical drug development that has significantly improved between 1995 and 2004 likely as a consequence of improved pharmacometric modeling and simulation.
The girls, on the other hand, and very likely as a consequence, move brightly to center stage.
Moreover, and most likely as a consequence of delayed ISV development, dorsal longitudinal anastomatic vessel (DLAV) development was also delayed in LCN7 injected embryos.
The results showed that Ad-cycE-infected ED-1 tumor cells were encircled in capsule-like structures and likely killed as a consequence of oncolytic Ad replication indicated by the high level expression of the viral hexon protein, forming vacuoles in the capsules.
However, results from several sources suggest that gene losses in the specialized tree symbiont T. melanosperorum and in the obligate plant pathogen B. graminis and the related powdery mildew genomes have taken place concurrently with, and are most likely as a consequence of, recently increased genetic drift (Bertault et al. 2001; Spanu et al. 2010).
Senescent changes in microglia may develop gradually over decades during human aging and likely occur as a consequence of multiple influences on the CNS microenvironment, notably free radical-mediated oxidative damage.
In female Dp10, most of the correlations seen in controls in the cerebellum are lost, leaving only levels of ERBB4 and AMPKA correlated, likely as a consequence of the perturbation of protein levels in this brain region.
Using western blot, immunoprecipitation, microscopy assays, and in silico analysis, we show results that strongly suggest that the increase in Aspirin-induced cytoplasm proteins acetylation reduced cell movement and capping formation, likely as a consequence of alterations in the structuration of the actin cytoskeleton.
Nonetheless, a significant number of books and papers by biologists and philosophers had sounded a warning about the loss of species, the possible impact of such losses on ecosystem functions and the reduction in value – both moral and economic – that was likely as a consequence of the reduction in natural variety (Norton 1986 and 1987; Wilson 1992).
However, plants expressing pga2 show stunted growth and reduced biomass production, likely as a consequence of an extensive loss of pectin integrity during the whole plant life cycle.
