Suggestions(2)
Exact(1)
Rapamycin has been shown to suppress mTOR activity, potentially decrease weight and fat mass, and extend healthspan and life span in a similar manner as calorie restriction [ 1- 4].
Similar(58)
This is the first demonstration of a neurotransmitter that inhibits insulin signaling in its regulation of metabolism, stress and life span in an invertebrate brain.
In a study by Baur and co-workers, resveratrol treatment has been demonstrated to improve health and life span in mice in the presence of a high-calorie diet (Baur et al. 2006).
In worms, miRNAs have been previously shown to regulate developmental timing and life span, in line with the idea of an intrinsic clock mechanism (33).
p66Shc protein plays a critical role in regulating oxidative stress response and life span in mammals.
Treatment with everolimus also decelerated tumor growth and prolonged life span in a mouse model of leiomyosarcoma.
Our findings demonstrate that mc-oriP-IFNγ induces antiproliferation of EBV-positive tumor cells, represses tumor growth, and prolongs the mouse life span in a manner as effective as that of mc-CMV-IFNγ in vitro and in vivo.
Another promising direction for future experiments will be to look at the interactions between sexual differentiation genes and the pathways and interventions that are known to regulate life span in a sex-specific manner, such as the insulin/IGF1-like signaling (IIS) pathway and dietary restriction (DR) [ 8, 10, 11].
In the present study we explore whether age- and sex-specific telomere dynamics affect life span in a long-lived snake, the water python (Liasis fuscus).
Therefore, it is not clear whether aging itself is a disease and how it would impact on life span in a protected environment.
In Drosophila curcumin have been reported to extend life span in a gender and genotype specific manner [ 39, 40].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com