Sentence examples for and lethality in a from inspiring English sources

It was shown that the oral administration of 17- allylamino -17-demethoxygeldanamycin 17- allylamino -17-demethoxygeldanamycin 17- allylamino -17-demethoxygeldanamycin 17- allylamino -17-demethoxygeldanamycinrodegeneration in an HD Drosophila model by induction of HSP70, HSP40, and HSP90 expression [ 227].

Finally, we report that simvastatin causes, in a dose-dependent manner, profound hepatotoxicity and lethality in mice fed a lithogenic diet.

Moreover, restoring InsP3R function in insulin producing cells (IPCs) in the larval brain rescues the feeding deficit, growth and lethality in the itpr mutants to a significant extent.

Infection caused by canine distemper virus (CDV) is a highly contagious disease with high incidence and lethality in the canine population.

This also increases the number of complications and lethality in surgery.

l-Leu treatment partially alleviates severe deformation and lethality in the cohesin morphant embryos.

In this study, we performed capsular serotyping, determined the presence of mucoid phenotype and aerobactin production, and assessed lethality in a murine model and correlated these in vitro and in vivo results with the clinical manifestation of patients with K. pneumoniae bloodstream infections.

Moreover, the advantage of our approach is that we could isolate genetic interactions in both directions, namely negative interactions such as synthetic lethal and dosage rescue and positive interactions such as synthetic rescue, phenotypic suppression, and dosage lethality in a single experiment.

This possibility is supported by the reports that simultaneous activation of Ras and Hh signalling caused extensive formation of intraepithelial neoplasias and accelerated lethality in a transgenic model of pancreatic carcinoma (Pasca di Magliano et al, 2006) and that de-regulation of Ras signalling in mice lacking p53 increased Shh expression (Hingorani et al, 2005).

Second, with the full consideration of back mutations, we study the equilibrium population distribution and the ancestor distribution in the genotype space as a function of error rate with and without lethality in a multiplicative fitness landscape.

The selective inhibitor of mammalian KCC, termed VU0463271, was found to be a potent inhibitor Ae. aegypti KCC and microinjection induced lethality in a concentration-dependent manner to susceptible and pyrethroid resistant strains.