Most of the international academic research also tends to involve looking at one-off and large-scale changes in police numbers, such as during a terrorist attack or a police strike.
While market forces clearly influence technology deployment, understanding the longer-term and large-scale changes in the energy system requires a broader understanding of the relative influence of institutional, behavioral, and social factors.
Varve thickness, varve thickness variance, ice-rafted debris, total organic carbon (mass flux and bulk concentration), and C N of sedimentary organic matter, reveal a dynamic late Holocene climate with abrupt and large-scale changes in ice-cap size and landscape stability.
In the hippocampus, both local changes in spine ultrastructure, and large-scale changes in spine morphology have been described in response to LTP induction [38].
JA and its metabolites elicit the expression of defense-related genes and large-scale changes in the transcriptome, proteome, and metabolome after leaf wounding and herbivory [1] [3] and is associated with a repression of growth and activation of defense-related processes [4] [7].
That said, challenges remain in trying to effect fundamental and large-scale changes in gender relations and patriarchal, violent masculinities.
Few mitochondrial gene rearrangements are found in vertebrates and large-scale changes in these genomes occur even less frequently.
Recent studies showed that the SV40 large T antigen gene or hTERT transfected immortalized cell line results in DNA hyper-methylation and large-scale changes in gene expression.
Despite the low sequence similarity between yeast and human Mediator, the overall structural organization and large-scale changes in its conformation appear to be well-conserved.
It is now recognized that ROS play an important role as signaling molecules which mediate changes in cell proliferation, differentiation, migration, invasiveness and large-scale changes in gene transcription [53], [54].
