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The most diversifying issues were related to internal validity-confounding criteria such as trials not being blinded or open-labeled, inadequate adjustment for confounding in estimating the effect of low-intensity exercise, and lack of reporting on participant attrition.
The confidence in our conclusions, however, is limited by the methodological shortcomings and lack of reporting clarity in many of the included papers.
We examined factors associated with accuracy and unavailability of parent-reported data and showed that length of time since parent last learned the child's height and weight is the main factor contributing to inaccuracy and lack of reporting.
Common poultry diseases occur frequently during the cold season, and lack of reporting of poultry deaths is of concern (4 ).
A number of systematic reviews (Cochrane: 86%; non-Cochrane: 49%) also assessed other methodological items, the most common being whether trialists had carried out an intention-to-treat analysis (n=29), evidence of baseline imbalance (n=27), funding source (n=26), small sample size (n=17), early stopping (n=12) and lack of reporting of a power calculation (n=11).
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Limitations of the study are short exposure duration and lack of report of iodine status of the subjects during the exposure.
Although a metabolic or immunologic defect may be necessary for illness to develop in dogs of various breeds after R. conorii infection, other potential explanations can be made for the discrepancy between high R. conorii seroprevalence rates among healthy dogs and lack of reports of clinical illness.
The large heterogeneity of studies and frequent lack of reporting the strength of alleged associations prevented us from providing measures of effect sizes.
Limitations of our measurements include the use of the central retinal field only and the lack of reporting absolute values for vessel length.
The entrapment of child marriage has left women and girls fearing for their lives as a result of social unwillingness to confront a culture of impunity to such violence and lack of official reporting.
Given the mixture of both positive and negative results, and lack of studies reporting no association, it is probable that selective publication has occurred.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com