Sentence examples for and its checkpoint from inspiring English sources

However, the cell cycle and its checkpoint systems can be sabotaged by defective proteins or genes that cause malignant transformation of the cell, which can lead to cancer.

In the present study, we showed that Baz is a critical player in centrosome orientation and its checkpoint in Drosophila male GSCs.

The road and its checkpoints were formalised in the 17th century (and immortalised in Hiroshige's wood-block print series 53 Stations of the Tokkaido in the 19th century).

He had not been fully briefed, but as soon as this mumbled announcement was broadcast on radio and television, tens of thousands of East Germans started to gather at the wall and its checkpoints, demanding that the border guards open the gates.

The process of DNA repair is inherently linked to cell cycle progression and its checkpoints.

New therapeutics strategies that aim at targeting the cell cycle machinery and its checkpoints are currently of a major interest.

Altogether, these observations reveal a previously unrecognized role for Pol κ during DNA replication in unperturbed cells, which appears to depend upon the catalytic activity of Pol κ, as demonstrated by a combination of depletion and complementation experiments, and support its checkpoint function in the absence of external stress, extending the role of this DNA polymerases outside the TLS.

A Hewlett-Packard spokeswoman said that the business has "policies that promote regular human rights risk assessments" and that its checkpoint products help "people to get to their place of work or to carry out their business in a faster and safer way".

Along with the URL Blacklist and the AVM, Facebook has ramped up security with the launch of its phishing reporting hotline [email protected] and its malware checkpoint.

However, in EWSR1 siRNA transfected cells, Aurora B localized at the area between chromosomes and central spindle (Figure 8 D c and f), indicating a mislocalization of the CPC complex and potential loss of its checkpoint function.

Although MEC1 is essential, both its checkpoint and telomere maintenance functions are dispensable for cell viability.