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The phrase "and its changes" is correct and usable in written English.
It can be used when discussing a subject that undergoes modifications or transformations, indicating the variations associated with it.
Example: "The study focuses on climate patterns and its changes over the last century."
Alternatives: "and the modifications" or "and the variations".
Exact(59)
It begins with an overview of the school lunch program and its changes over time.
We determined the multilayer period and its changes with temperature from X-ray reflection.
A link is made to the A-pillar vortex and its changes in intensity.
Surface morphology and its changes are registered with scanning electron microscopy (SEM).
Techniques to adequately estimate fat-free mass and its changes over time are needed.
We estimated the prevalence of vision impairment and its changes worldwide for the past 20 years.
Cave profiles and levels reflect the local fluvial base level and its changes through time.
The proposed sensor is capable of measuring rotating shaft angular speed, and its changes.
This study was performed to evaluate the metabolic syndrome status and its changes through menopause.
We used SDI to quantify the degree of degradation and its changes in space and time.
Similar(1)
None of the previous studies investigated sputum cellularity and its changes after airways clearance treatment.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com