The phrase "and its alteration" is correct and usable in written English.
It can be used when discussing changes or modifications made to something, often in a formal or academic context.
Example: "The study examined the original document and its alteration over the years."
Alternatives: "and the changes made" or "and the modifications".
Gating within limbic cortical circuits and its alteration in a developmental disruption model of schizophrenia.
Distribution of N-acetylaspartylglutamate immunoreactivity in human brain and its alteration in neurodegenerative disease.
Growth of the normal skull vault and its alteration in craniosynostosis: insights from human genetics and experimental studies.
The cell wall is a barrier that hinders pathogen invasion and its alteration acts as a source of signaling to activate the plant defense response50.
The present study was designed to investigate the expression of inducible NOS in normal and neoplastic urothelium and its alteration following tumor resection and subsequent intravesical immunotherapy.
Tubulin proteomics complements structural and computer modeling information for a high-resolution view of microtubule dynamics and its alteration by drugs.
By modulating these pathways, BAG3 appears to mediate cell adaptive responses to stressful stimuli, and its alterations result in altered homeostasis and reduced cytoprotection, explaining why its expression is often found deregulated in a vast series of tumors.
It hardly heals spontaneously and its alterations often lead to further extracellular matrix degradation and ultimately, to the loss of joint function.
Afterwards, it was shown that chromosome 17 and its alterations are important markers to stratify patients with respect to their prognosis [ 8].
One of the primary advantages of high-throughput RNA sequencing (RNA-Seq) is that it enables accurate assembly of the transcriptome, and its alterations across experimental conditions, so as to allow prioritization of the transcripts and splice forms that are potentially most relevant to the observed phenotype.
