Sentence examples for and investigate the functionality from inspiring English sources

Here we sought to identify and investigate the functionality of T-UCRs differentially expressed in NB cell lines following ATRA-treatment.

In this study, we generated iPSCs from a patient with dilated cardiomyopathy (DCM) caused by a missense mutation S635A in RNA-binding motif protein 20 (RBM20) and investigated the functionality and cell biology of cardiomyocytes (CMs) derived from patient-specific iPSCs (RBM20-iPSCs).

It upregulates p53 without the need for upstream signaling events, and allows to investigate the functionality of downstream p53 signaling in senescent cells.

We have used rat ClC-7 in CHO cells as a model system to investigate the functionality and cellular localization of the wt transporter and its variant G213R ClC-7 which is the analogue of human G215R ClC-7 responsible for autosomal dominant osteopetrosis type II.

To investigate the functionality and contribution of the SERCA pumps to whole-cell [Ca2+]i transients through their ability to reload the SR Ca2+ stores in hiPSC-CMs we applied the SERCA inhibitor thapsigargin.

Because CB2 receptors have been found to signal through Ca2+, we used calcium imaging and extracellular and intracellular administration of cannabinoid ligands to investigate the functionality of plasmalemmal versus intracellular CB2 receptors in U2OS cells stably expressing CB2.

The drug release profile, MC3T3-E1 cell proliferation and alkaline phosphatase activity were used to investigate the functionality of these hybrid coatings.

To investigate the functionality of β1 and α2 integrins, which were strongly elevated in PC3res, compared with PC3par cells, blocking studies were carried out.

To investigate the functionality of BoFRIa-1 and BoFRIa-4 alleles under different environmental conditions five transformants carrying each allele were analysed in the next (T2) generation.

In order to determine collateral conductance a method previously established and validated for the rabbit hindlimb was adapted to investigate the functionality of collateral vessels in the rat hindlimb at maximal vasodilatation [ 22].

To investigate the functionality of T. pseudethanolicus AdhE and AdhB in C. bescii, strains were characterized in LOD medium supplemented with 40 mM MOPS and 1 % (wt/vol) cellobiose.