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Furthermore, the current findings have important implications for the design and interpretation of developmental studies of ERPs indexing language processing, and they highlight the need to take into account cognitive abilities both within and outside the classic language domain.
We review pharmacokinetic and pharmacodynamic factors that should be considered in the design and interpretation of developmental neurotoxicity studies.
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This "Ecdysozoa" hypothesis has influenced diverse fields [ 4] and interpretations of developmental evolution in animals [ 5- 7].
The European Teratology Society and Health and Environmental Sciences Institute co-organized a workshop to consider best practices, including data quality and consistency, interpretation of developmental effects in the presence of maternal toxicity, human relevance of animal data, and limits of chemical classes.
The reliable detection, measurement, and interpretation of treatment-related developmental neurotoxicity (DNT) effects depend on appropriate study design and execution, using scientifically established methodologies, with appropriate controls to minimize confounding factors.
Models of movement coordination and control provide the frameworks necessary for the design and interpretation of studies of acquired and developmental disorders.
In general, the article makes a point we heartily agree with, namely that the standard logic of neuropsychological interpretation should not be applied uncritically to the interpretation of developmental disorders.
Interpretation of developmental effects in p53-deficient models at the organismal level are complicated by the overlapping transcriptional functions of the p53 family members p63 and p73 [ 58] which include such vital targets as p21Waf1/Cip1, Bax and MDM2 and likely other unknown target genes.
Altogether, the position of Polycladida recovered in our analyses suggests that the order may be more derived within Platyhelminthes than has been widely appreciated, warranting particular caution in the interpretation of developmental data from the only platyhelminth taxon amenable to experimental embryological research (Boyer et al., 1998; Rawlinson, 2010; Lapraz et al., 2013; Rawlinson, 2014).
This chapter discusses the clinical administration and interpretation of the Bayley-III, outlines its strengths and weaknesses, and provides a case study that highlights its use with a toddler who displays developmental delays.
led the analyses and interpretation of data.
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