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Objective: Our goal was to investigate the short-term and intermediate effects of low-dose hormone replacement therapy on echocardiographic parameters of cardiac function in healthy postmenopausal women.
Tests for associations between immediate and intermediate effects of orphanhood and psychological distress showed strong positive associations for: (a) living in a household with a recent death; (b) living in a household with a seriously ill adult member; (c) suffering stigma; (d) inadequate care; (e) child labour; (f) physical abuse; and (g) being out of school (Table 2).
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Dichotomous variables were created for each moderating factor and immediate and intermediate effect of orphanhood.
The case of research grant funding, involving a complex mix of direct and intermediate effects that contribute to the overall impact of funding on research performance, illustrates the value of a mixed methods approach to provide a more robust and complete analysis of policy impacts.
The 'small theory of improvement' is the theory about the sequences of actions and intermediate effects which may lead to improvement in the ultimate clinical outcomes.
The maximal effect was observed at the highest concentration (10 mg/kg/day)) and intermediate effects were found at the doses of 2.5 and 5 mg/kg/day and 2(c)).
Single-QTL methods, as our ACF case suggests, in fact, ignore QTL of minor and intermediate effects, which may be linked or epistatic such that genotype at one QTL can dramatically influence QTL effects at other loci [ 44, 45].
An intermediate telephone survey after two intervention components (week 25) was used to assess all participants' behaviors and determinants to gather the most recent information for the computer-tailored intervention and assess the intermediate effects of the interventions.
Nevertheless, as the regression analysis and sensitivity analysis showed little or no effect of MetS and total cholesterol, substantial intermediate effects of diet is unlikely.
Walton and colleagues (2014) examined the intermediate effects of a single-session, computerized or therapist-delivered brief intervention on psychological constructs hypothesized to be key moderators of behavior change.
The advantages of the latter approach are obvious: the correct implementation of the technique is guaranteed, it can be suited to the characteristics of each subject and it is possible to detect possible intermediate effects of the procedure, among other possibilities.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com