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Considering that some factors play critical roles in biological processes and interact with abundant related genes or proteins, the top hits proteins were sorted and assessed from protein-protein interaction (PPI) network.
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Therefore, we hypothesize that condensin may have to interact with abundant pol II transcripts before faithful segregation of postreplicative chromosomes.
Transcription factors bind to regulatory elements upstream of transcription start sites and interact with other factors to create an abundant regulatory environment.
Two isoforms of spastin, 68 and 60 kDa, respectively, are variably abundant in tissues, show different subcellular localizations and interact with distinct molecules.
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