The phrase "and indicate a substantial" is correct and usable in written English.
It can be used when discussing evidence, findings, or results that show a significant amount or degree of something.
Example: "The research findings are expected to support the hypothesis and indicate a substantial improvement in patient outcomes."
Alternatives: "and demonstrate a significant" or "and show a considerable".
The average timber volumes are consistently below 350 m3/handnd indicate a substantial reduction of the initially high timber volumes in southern Germany.
The average timber volumes are consistently below 350 m/ha and indicate a substantial reduction of the initially high timber volumes in southern Germany.
These data are consistent with the echocardiographic measurements and indicate a substantial degree of systolic and diastolic dysfunction in PLM3SA mice after aortic constriction.
No differences were found when analyzing the results on EQ-5D-Y according to language, which likely reflects the bilingual characteristics of the sample and indicate a substantial level of agreement between the Catalan and Spanish versions of EQ-5D-Y.
Merrill's index of bonds rated CCC or lower — the very bottom of the credit pool and indicating a substantial risk of default — has gained almost 75percentt in 2009, adjusted for inflation.
To show the reproducibility of the relationship features between tophi and tendon, the data were analysed and indicated a substantial inter-observer agreement between the radiologists, with a kappa index result of 0.627 (P < 0.001) and McNemar-Bowker test (chi-squared equal to 30.0 with P < 0.001).
Microarray analysis revealed non-overlapping downstream transcriptional targets of MEK1 and MEK2, and indicated a substantial rescue effect of MEK2cr on proliferation pathways.
The comparison of different models of diversification using Bayes factor tests led to the selection of a two-rate pure-birth process and estimated a fourfold decrease in speciation rates (dropping from an initial 0.441 to 0.108), and indicating a substantial slowdown during the Miocene.
For interpretation, HIT-6 scores are categorized in four groups: scores of ≤49 indicate little or no impact; scores between 50 and 55 indicate some impact; scores between 56 and 59 indicate a substantial impact; and scores ≥60 indicate a severe impact [22].
For interpretation, HIT-6 scores are categorized in four groups: scores ≤49 indicate little or no impact, scores between 50 and 55 indicate some impact, scores between 56 and 59 indicate a substantial impact, and scores ≥60 indicate a severe impact [27].
However, bioinformatics analyses of human and mouse genomes indicate a substantial impact of TEs on cellular gene regulation; as many as 25% of genes possess TEs in their UTRs [8], [48].
