With the requirement of mating per generation (that is, disease transmission) and selective pressure being rare to discriminate intra- versus inter-species mating, diversification by positive selection may not be expected at the mating pheromone and receptor, and indeed the patterns observed here were strongly purifying.
Although not investigated, this was presumably due to physician's skill up in chemotherapy rather than the change of patient characteristics, and indeed the referral pattern did not change during the study period.
This can only be explained if the recombination event is ancient, and indeed the breakpoint patterns affected all members in particular groups, suggesting that the events pre-dated the divergence of the different groups.
"I remember there was a discussion: 'Headphones can't be white; headphones are black, or dark gray".' But uniform whiteness seemed too important to the product to break the pattern, and indeed the white headphones have become a kind of secondary, unplanned icon -- as Apple's current ads featuring white-headphoned silhouettes now underscore.
Indeed, the pattern and expression levels of PP1γ declined with an almost linear relationship from normal tissue, through increasing grades of CIN lesion, to invasive cancer.
Indeed, the pattern of loss is similar between LCA1 and Blochmannia, LCA1 and Wigglesworthia, LCA1 and the common ancestor of B. aphidicola strains (LCA3) or LCA1 and LCA2.
Indeed, the pattern of alternation of Rad21L and REC8 on meiotic chromosomes creates an appearance of a "barcode" [ 31, 32].
Indeed, the pattern of manifestation of signs and symptoms should not be presumed to coincide with the timing of etiologic factors.
Indeed the pattern was for further decreases at the hip and, in those who had received the calcium supplement during pregnancy, at the distal radius and whole body.
In addition, children's familial predisposition to obesity may differentially affect their beverage consumption patterns and indeed the risk of overweight and obesity.
