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The phrase "and indeed a substantial" is correct and usable in written English.
It can be used to emphasize the significance or importance of something in a statement or argument.
Example: "The research findings were, and indeed a substantial, contribution to the field of environmental science."
Alternatives: "and certainly a considerable" or "and truly a significant".
Exact(5)
Yet they are both cities of around 140,000 people, with large tourist populations and, indeed, a substantial crossover in their film tastes.
But Bertie Ahern, the Irish prime minister, when asked on Sunday if the various IRA statements and, indeed, a substantial act of decommissioning had created a context in which Sinn Féin was now a viable partner in an Irish government, said that the republican movement had still not reached that point.
And indeed, a substantial amount of variation in outcome of exposure to N. whitei was explained by such main effects in both parties (Table 1).
Unlike the catalytic interface, however, the secondary patch is interspersed with residues which, when mutated, had no effect on oligomerisation, and indeed a substantial part of the secondary patch area could be replaced simultaneously without preventing oligomerisation (data not shown).
We showed previously GeneMANIA's results (with the normalization) are strongly affected by node degree, and indeed a substantial fraction of performance as measured by ROC curves could be explained by node degree effects.
Similar(55)
Those of us agitating most for Mr. Obama's election saw the speech for what it was: an attempt to notify the world that this version of America will not last much longer and that, indeed, a substantial portion of our nation sees the urgent need for shared vision and purpose in place of superficial challenges to would-be opponents.
The time evolutions of the intersubunit distance (d), angle, and interfacial contact in the course of the AA and CG simulations are shown in Fig. 4, A – C. The plots show that first, the subunit arrangement is asymmetric and there is indeed a substantial intersubunit movement.
Fan, Local linear smoothers and their minimax efficiencies, The Annals of Statistics 21 (1993) 196 216] was found to dominate, and indeed offers a substantial advantage in various situations, even when the error term has a heavy-tailed distribution.
Indeed, a substantial proportion of sportsmen and women who compete at the elite international level have a diagnosis of asthma [ 26] or experience exercise-induced asthma [ 9].
The results show that there is indeed a substantial intersubunit movement (translational and rotational) that allows dynamic exposure of the active site in each subunit, albeit to various degrees.
The analysis of the AUC and BEDROC optimized queries showed that the optimized VS metric has indeed a substantial influence on the resulting weights and the performance.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com