The phrase "and in the systemic" is grammatically correct and can be used in written English.
It can be used in contexts discussing systems, structures, or processes, particularly in fields like sociology, biology, or organizational theory.
Example: "The research focuses on the factors affecting behavior and in the systemic analysis of social interactions."
Alternatives: "and within the system" or "and in the systemic context".
Salicylate (SA) disposition in the skin and muscle as administration sites, and in the systemic circulation were evaluated following intracutaneous (i.c).
(1) Mechanical ventilation can change the metabolic profile in the lung and in the systemic compartment.
Our data show that the rigors of exercise directly induce fibrinolytic genes and protein cascades, both within muscle, and in the systemic circulation.
Acute lung injury induced by mechanical ventilation [ventilator-induced lung injury (VILI ]is characterized by a particular metabolic profile in the lung and in the systemic compartment [1].
Notably, knockout of AT1 receptors on T lymphocytes exacerbated the severity of cisplatin-induced AKI and enhanced the cisplatin-induced increase in TNF-α levels locally within the kidney and in the systemic circulation.
The inflammation-associated cytokine Interleukin-6 (IL-6) is increased in the biliary tract and in the systemic circulation in patients with cholangiocarcinoma [12] [15].
During cardiac surgery and cardiology interventions, microemboli may be generated and disperse in the systemic circulation.
Polyphenols that reach the colon are extensively transformed by the microbiota; and their main products, phenolic acids, are themselves absorbed and found in the systemic circulation.
Moreover, deactivation in plasma and strong protein binding (around 98%) minimize the adverse effects of LE and ED in the systemic circulation.
Together, these data suggest that cancer results in decreased cDC lineage cells in the BM and decreases in the systemic pool of pre-DCs.
However, it is worth mentioning again that absorption and availability in the systemic circulation is not necessarily an indicator of presence or duration of action at a receptor.
