The phrase "and in the surrogate" is grammatically correct and can be used in written English.
It can be used in contexts discussing alternatives, substitutes, or representatives, particularly in legal, medical, or social discussions.
Example: "The results were analyzed both in the original study and in the surrogate to ensure consistency."
Alternatives: "and in the substitute" or "and in the proxy".
A surrogate outcome will be reliable only if there is a validated causal connection between change in surrogate and change in the clinically important outcomes (like morbidity and mortality), and if the surrogate reflects most of the effects of treatment on a specific outcome.
This process was repeated 500 times, determining the significance based on the ranking of the SC and NC in the surrogate distributions (two-tailed, p<0.01).
The discrepancies observed in reported associations between IR and SVR may reflect homogeneous patient populations with limited ethnic diversity; variation in host factors that are well known to affect IR, such as BMI; and limitations in the surrogate measurements of IR compared with direct measurements.
Mr. Dadakis, who is representing Mr. Bock and Mr. Kamsler in the surrogate's court proceeding, said that both men had done what Mrs. Clark had asked of them, and that she left them money because they were close to her. "When you understand who Mrs. Clark was," Mr. Dadakis said, "I think you clearly see that this is a lady that was very strong willed.
It is for these women that the Panel believed that the approach adopted by successive St Gallen Panels based on the available clinico-pathological testing, and now expressed in the surrogate IHC-based classification shown in Table 2 will be more widely applicable at lesser cost, notwithstanding its limited validation.
Where once politicians' children were generally left alone, today we are reporting on the contract between Mitt Romney's son and daughter-in-law and the surrogate they chose to have their children.
The spatially resolved measurements of soot and fluorescent soot precursors are quite identical (in shape and intensity) in the Diesel and in the second surrogate flames.
Lastly, the use of surrogate end points has been criticised and it has been suggested that surrogate outcomes should not been used without validation studies proving that the treatment effect of interest is the same in the surrogate and in the endpoint of clinical importance [ 25, 26].
For the surrogate definitions and for endocrine responsiveness, we only show the curves for the ER+/HER2−, as the triple negative and HER2+ subtypes are similar in the surrogate subtype definitions to the IHC-subtypes.
