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Annual rainfall averages 35 to 45 inches, with marked seasonality of occurrence and considerable fluctuations from year to year, both in total rainfall and in the onset of rainy periods.
Growing evidences indicate that proteases are implicated in adipogenesis and in the onset of obesity.
Such impairments may then play a role in the development of abnormal gait and in the onset of plantar ulcers.
Failure to account for how the increase in body weight could affect the respiratory function can result in injurious mechanical ventilation and in the onset of VILI.
Our data demonstrate a role for the TGFβ/ALK5 signaling pathway in the regulation of EMT of human adult epicardial cells and in the onset of differentiation.
Since 2008, several studies have been conducted to clarify the contribution of autophagy alterations in establishing chronic HCV infection and in the onset of associated diseases [ 47– 47].
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The pro-inflammatory cytokines attack the myelin and axon, consequently, demyelination and axonal injury occur and result in the onset of MS/EAE [ 8].
30 IL-10 is a potent inhibitor of the production of proinflammatory cytokines and chemokines implicated and involved in the onset of inflammation.
In summary, our data suggest potential roles of Akt, Foxo3a and Sirt2 in the onset of diabetic cardiomyopathy and the therapeutic potential of catalase.
Inflammation plays an important role in atherosclerosis development and progression as well as in atheromatous plaque rupture and, thus, in the onset of acute clinical complications [ 1].
c-jun N-terminal kinase 1/stress-activated protein kinase 1 (JNK1/SAPK1) is activated during I/R and participates in the onset of the apoptosis program.
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