The phrase "and in the onset" is not correct in standard written English.
It seems to be a misphrasing; the correct expression would typically be "at the onset."
Example: "At the onset of the project, we faced several challenges that needed to be addressed."
Alternatives: "at the beginning" or "in the initial phase."
This interplay between energy metabolism and ROS becomes most apparent during the aging process and in the onset and progression of many age-related diseases (i.e. diabetes, metabolic syndrome, atherosclerosis, neurodegenerative diseases).
Annual rainfall averages 35 to 45 inches, with marked seasonality of occurrence and considerable fluctuations from year to year, both in total rainfall and in the onset of rainy periods.
N-methyl-D-aspartate (NMDA) receptors, have an established role in mechanisms of central sensitization [9, 10] and in the onset and propagation of cortical spreading depression [11, 12]; in addition, an association has been found between migraine and polymorphisms in genes involved in the regulation of synaptic Glu uptake and postsynaptic Glu signaling [13 15].
Growing evidences indicate that proteases are implicated in adipogenesis and in the onset of obesity.
We find that an ensemble of cells produces a distinctly heterogeneous response to the AI input, with significant cell-to-cell variability in the overall level of emission and in the onset time for this response, as well as indications of short term fluctuations in brightness.
Furthermore, distinct ADAMTS subtypes have also been shown to play integral roles in the growth and development of tissues and in the onset and progression of degradative diseases including cancer [9] [11], arthritis [12], Alzheimer's disease and a number of inflammatory and thrombotic conditions [13], [14].
Natural and philosophical foundations of political violence; the potential roles of ethnicity, economic factors, territory, and political institutions and structures in the onset and dynamics of civil conflict; problems of conflict termination.
This suggests a link between the brain and periphery in the onset and development of the disease.
Moreover, NK cells are major cytokine producers and participate in the onset and shaping of the adaptive immune response.
Involvement of epigenetics and microRNAs in the onset and survival signals of lung cancer are also mentioned.
In a complementary manner, the key role of ECM composition and remodelling in the onset, progression and severity of IBD has been implicated in various rodent models.
