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This review highlights the fundamental aspects of HSPs in protein folding and quality control, in the elicitation of a stress response in connective tissue and in the characterization of HSP47 in collagen folding and assembly.
Previous studies concerning PAM in rodents have focused in congenital malaria [24] and in the characterization of placenta pathology [25], [26].
Interestingly, P-gp expression has been associated with outward proton movement and intracellular alkalinization as a consequence of increased Cl−/H+ antiport [47]; similar data were also obtained in the analysis of human P-gp over-expression in yeast cells [48] and in the characterization of a bacterial P-gp homologue [49].
The dataset has already been used in conjunction with genome-wide association studies and in the characterization of tetraspanins.
Moreover, it is critical to mention the primordial role played by the transgenic mouse models in the development of tracers for magnetic resonance imaging (MRI) and positron emission tomography (PET) imaging and in the characterization of new biomarkers [ 15, 16].
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MKH isolated and mapped the KIAA0574 gene and participated in the characterization of APBA2.
The role of perfusion, permeability and MRS in the characterization of tumor biology and different pathologies is reviewed[ 2 4].
The estimated parameters were easy to interpret, and aided in the characterization of gene expression and co-expression profiles.
MLR: constructed and participated in the characterization of high-complexity cDNA libraries, and participated in the development of selection criteria for genes included on the 16006-gene microarray.
Therefore, it helps microbiologists and pathologists in the characterization of new strain isolated from various sources.
This chapter is a compendium of facts, challenges and opportunities in the characterization of biomedical polymers.
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