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21 22 There is a difference, however, between implementation of clinical knowledge and implementation of methodological knowledge.
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The design and implementation of an RCT require methodological as well as clinical expertise, meticulous effort, 143 308 and a high level of alertness for unanticipated difficulties.
Although the number of economic evaluations of pharmacoeconomic guidelines has increased, the use of economic evaluations in other jurisdictions usually requires the implementation of methodological adaptations for the specific environment under investigation [ 2, 3].
The objective of this study is to propose the design and implementation of voxel-based automata as a methodological approach for representing spatial processes evolving in the four-dimensional (4D) space time domain.
This paper is a preliminary methodological study and implementation of non-destructive techniques for the study of fragile objects for which sampling is prohibited.
We recognize that the design and implementation of our study may have certain methodological limitations.
Details of the methodological design and implementation of individual evaluations can be found in each of the nine sections of the report.
The paper also furnishes a set of methodological guidelines exploitable for the design and implementation of smart city applications by properly using iSapiens.
Basic conceptual and methodological issues for the design and implementation of coordination experiments in the context of neuroimaging are discussed.
Methodological considerations in the design and implementation of clinical trials.
Therefore, broader promotion of methodological quality guidelines is a necessary step in enhancing dissemination and implementation of AMSTAR and MOOSE.
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