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Here, we propose that simply replacing the collagen I matrix employed in the standard Caco-2 assay with an engineered matrix, we can control cell morphology and hence regulate the cell-cell junctions that dictate paracellular transport.
Fine-grained particles act as an efficient scavenger and hence regulate transport and sediment accumulation of heavy metals in rivers and streams (Zonta et al. 1994; Sharmin et al. 2010; Mohiuddin et al. 2010).
Protein-protein interactions, such as those between inactive ROP and ROP GDI [41], or between active ROPs and membrane- or cytoskeleton-associated proteins, are also likely to alter ROP mobility, and hence regulate the localization of patches.
It has been shown to activate NFκB and hence regulate IL-8 expression.
This domain of p53 is known to accommodate several post-translational modifications, which, at least theoretically, can modulate its ability to bind (and hence regulate the activity of) SERCA.
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In addition, these proteins are known to play a role in the regulation of DNA-topology, stabilising chromosome compaction and, hence, regulating gene expression [ 82].
These factors influenced the intensity of chemical weathering and hence regulated the volume and composition of clastics delivered to the depocentre.
ZCCHC11-dependent uridylation of mature cytokine-targeting miRNAs is known to lead to the stabilization of cytokine transcripts and hence regulates cytokines gene expression.
Our prior expectation was based on the redundancy mechanism by which one of two genes involved in the same process (and hence regulated by the same TF) suffices at any point in time.
Although 4E-BPs do not bind RNA, multisite phosphorylation of these proteins controls protein protein interactions at the m7G cap on the 5′ end of the mRNA and hence regulates translation initiation.
The activities of FLS, F3'5'H, DFR, and possibly F3'H, hence regulate the distribution between flavonols and anthocyanins in tomato plants.
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