The phrase "and have substantial implications" is correct and usable in written English.
It can be used when discussing the potential effects or consequences of a particular action, decision, or event.
Example: "The new policy changes are expected to affect the entire organization and have substantial implications for employee morale."
Alternatives: "and carry significant consequences" or "and have considerable effects."
The observed geographic distributions of SES and genetic variation relate to historical social events and mating patterns, and have substantial implications for the design of studies in the recently admixed Puerto Rican population.
Previously published research by the authors has also found that student beliefs around the role of mathematics in science are well established by the time they reach university and have substantial implications for how quantitative topics are taught in first-year science (Matthews et al., 2009).
These findings highlight the importance of the CREB pathway in many aspects of OVCA phenotypic behaviour and may have substantial implications for the future direction of research into disease development, response to therapy, and clinical outcome.
Such low malaria indices at health facilities and in communities have substantial implications for policies on health resource allocation and control or future elimination of the disease.
Our observations and our optimization approach have substantial implications for designing safe and effective artificial transcription factors for cell-based and therapeutic uses.
Unreliability is inevitably imposed by non-idealities in the physical communication channel, and this unreliability will have substantial implications for those seeking to convey interstellar messages.
Because regional patterns of medical practice are similar for Medicare and non-Medicare patients, the findings have substantial implications for America's health care system.
In sub-Saharan Africa, the emerging co-occurrence of type 2 diabetes mellitus and tropical infectious diseases thus may have substantial implications.
Thus, even if a discussion of national impacts of national and European policies is inevitable, they can have substantial implications on adjacent regions through the interconnected electricity system.
Projections of pyrogenic C emissions and the effects of forest treatment on fire behavior can have substantial implications for projecting future forest C balance and therefore this is an area of research that deserves careful analysis in the future.
