The phrase "and generating a substantial" is correct and usable in written English.
It can be used in contexts where you are discussing the creation or production of something significant, often in terms of quantity or impact.
Example: "The new marketing strategy is expected to increase sales and generate a substantial profit for the company."
Alternatives: "and producing a significant" or "and creating a considerable".
How can we twist and tie enough pieces together so that the health care needs of the many are balanced out by the concerns of this vast economic sector that employs countless people all across the country and generates a substantial portion of our gross national product?
Selection criteria were that the therapeutic groups should encompass both substitutable and non-substitutable pharmaceuticals, be widely used in outpatient care and generate a substantial cost to society.
Leukemia cells were allowed to proliferate and generate a substantial tumor burden before the start of treatment with phosphate-buffered saline, nilotinib, AMD3100, or a combination of nilotinib and AMD3100.
Plasmodium vivax, the second malaria species in terms of epidemiological importance but less deadly than P. falciparum, causes ~ 70 80 million clinical malaria cases annually with 2.85 billion people living at risk of infection (Guerra et al., 2010) and generates a substantial economic burden worldwide.
Last month's earthquake in the New Zealand city has forced the administrators to think differently about the fixture schedule, and if this game succeeds in capturing northern hearts and minds while generating a substantial six-figure sum for charity, it will be considered a worthwhile venture, albeit one forged in the fires of tragedy.
The α-dystrobrevin gene is subject to complex transcriptional and post-transcriptional regulation, generating a substantial range of isoforms by alternative promoter use, alternative polyadenylation and alternative splicing.
Free from the need to appear neutral and not to offend readers, and free from the need to keep close working relationships with news subjects, bloggers were able to identify something that grated on their sensibilities, talk about it, dig deeper, and eventually generate a substantial intervention into the public sphere.
Dorset's three ports, Poole, Weymouth and Portland, and the smaller harbours of Christchurch, Swanage, Lyme Regis, Wareham and West Bay generate a substantial amount of international trade and tourism.
Unless GMG is prepared to actually fund some full time journalists here to investigate some of the real issues which afflict this country but never get attention (and I could generate a substantial list) then you are going to be simply reheating and rehashing stories - as some of this weeks stories have already done eg poor regional health services.
