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It has been shown that hotspots are tumor-specific and, furthermore, include both residues that are directly involved in DNA-binding and residues that are important for maintaining the conformation of the p53 protein [ 14].
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Originating in the initial optimization of well-defined functions, logistics developed into the optimization of cross-functional activities and processes and, furthermore, includes value chains through design and optimization of global networks today ([24]; [24].
While at the Lindau Test Site insufficient overburden represents a criteria of exclusion for the existing design of the tunnel, at Äspö HRL the general stress situation is unsatisfactorily described and furthermore includes most likely thrust faulting.
In the case of KIN11, the interactome network contains 47 and 18 total interactions with any confidence and low confidence level, respectively; this is similar to the KIN10 interactome, and furthermore includes phosphatase, sugar transporters and cyclic nucleotide-gated channels (Fig. 2, Table 4).
Telecare training should furthermore include considerations of professional accountability, risk assessment and risk management related to its use [ 35, 36].
Ubiquitylated targets furthermore include structural proteins (4.4%), components of the immune system (4.2%), and transporters of small molecules (2.3%).
We furthermore include in this article a detailed account of this scientifically based training programme.
Obesity and overweight are considered key risk factors for type 2 diabetes incidence especially in youth, and were furthermore included as outcome parameters, but were analysed separately.
In this view, expert knowledge resulted from a reorganization of intuitive (naïve) knowledge, and expert knowledge furthermore included intuitive ideas (diSessa, 1993; Smith et al., 1993/1994).
In both cases, removing two traits did not affect the predicted timing of the remaining 14 traits in the analysis (A and B ). Furthermore, including two additional traits associated with C4 photosynthesis also did not alter the predicted timing of other traits (C ).
Furthermore, including all transcripts and not only polyadenylated RNA would give amore complete overview of the RNA population in a given cell type.
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