Wei et al. [ 43] has reported that DTH8 QTL for days-to-heading encodes a putative HAP3 subunit for the trimeric HAP2/HAP3/HAP5 complex and suppresses flowering in LD, and further speculated that the formation of the Hd1/DTH8/HAP5 and Ghd7/DTH8/HAP5 complex might be associated with the suppression of flowering by the downregulation of Ehd1 and Hd3a in LD.
Leppäluoto further launched the idea that the temporary imbalance of the vaginal microflora towards a BV-like profile serves sperm survival and transport, and further speculated that this imbalance is actually physiological in nature, if the microflora is allowed enough time to recover following a coital act [ 94].
We extend the observations by generation of iPS cells, and further speculate that lamin A depletion in the nuclear envelope might facilitate movement of telomeres, accessible for telomere elongation associated proteins, as well as amenable for recombination to elongate telomeres, essential for maintenance of pluripotency of iPS/ES cells.
On an inspection of the January 1527 census of the Regula quarter, in which one Io Leo is counted as head of a household of three persons, Davis speculates that Leo married and had a child, and further speculates he married a mora (that is, a converted Muslim woman).
Locke says that the survivors call it "The Monster", and further speculates that The Monster may be what brought them there and that Eko died for a reason, he just does not know what it is yet.
Okamoto and colleagues further speculated that another potential reason for the discrepancy between the two studies might have been imaging time post-injection and considered imaging at 4+ h to be more suitable, due to slow clearance of FMISO from the blood [19].
Because of the close relations between the serotonergic, noradrenergic, and dopaminergic systems, we further speculated that a general mechanism would link monoaminergic tone and emotional reactivity in this specific region.
First generation GSMs have been hypothesized to interact with the substrate, the secretase, or both [ 22], and it has been further speculated that, in the instance of modulators targeting the APP and Aβ sequences, this might affect the processing by adjusting the position of the amino acid sequence in relation to the membrane [ 38].
In conjunction with the cellular proliferation and invasion induced by Res in vitro, we further speculated that Res could decrease the expression of YKL-40.
It therefore can be further speculated that hyperglycaemia, which in turn predisposes to a proinflammatory and proatherogenic state is essential for the adverse impact of TCF7L2 on atherogenesis.
Based on the abovementioned conditions, the content variation of anthraquinone glycosides was further speculated to relate with altitude increase, which lead to temperature drop and glucose accumulation, resulting in the difference of biosynthesis and accumulation of anthraquinone glycosides.
