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Mueller, S.N. & Germain, R.N. Stromal cell contributions to the homeostasis and functionality of the immune system.
Mueller, S. N. & Germain, R. N. Stromal cell contributions to the homeostasis and functionality of the immune system.
However, fundamental differences in genomic organization and functionality of the immune system have been found in teleost lineages.
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However, composition of the intestinal microbiota may also vary in elderly subjects independently of diet because of a number of physiological and immunological factors, such as reduced functionality of the immune system.
Age-related physiological changes in the gastrointestinal tract, as well as modifications in lifestyle, nutritional behaviour, and functionality of the host immune system, inevitably affect the gut microbiota, resulting in a greater susceptibility to infections.
Furthermore, these genes formulate an important genetic functionality of the immune system, which illustrate the relationship between schizophrenia and autoimmune diseases.
Research in ecologic immunology has shown that the functionality of the immune system has to be considered in an ecologic and evolutionary life-history context.
Moreover, the age-related decline in the functionality of the immune system (immunosenescence) [5] is characterized by a chronic low-grade inflammatory status (inflammageing) [6] [8].
This is particularly important when proposing their possible use as drug delivery devices in tumor-bearing patients for whom the maintenance of an appropriate functionality of the immune system is of crucial importance for the benefit of the antitumor therapies.
SNPs alter the phenotype and functionality of proteins in the immune system thereby affecting its function leading to disease.
Classifying interconnected and overlapping components of the immune system into subsets, according to their functionality, such as cellular versus humoral immunity or innate versus adaptive immunity, permit the complex immune system to be dissected into distinct areas.
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