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The structural and functional interaction between D2 dopamine receptor (DR) and A2A adenosine receptor (AR) has suggested these two receptors as a pharmacological target in pathologies associated with dopamine dysfunction, such as Parkinson's disease.
In conclusion therefore, we have demonstrated physical and functional interaction between protein kinase A and HSF1.
We provide evidence of a physical and functional interaction between the products of these two genes, which are mutated in two distinct renal ciliopathies, polycystic kidney disease and nephronophthisis, supporting the notion that the molecular mechanism underlying cyst formation shares common pathogenetic dysfunctions in different diseases.
The enrichment of cognate seed matches in computationally predicted favorable contexts and the correlation between specific miRNA-dependent Ago2-IP enrichment and changes in mRNA levels are strong evidence that the assay reflects a direct and functional interaction between the transfected miRNA and the Ago2 IP-enriched mRNAs.
In this study we have identified a physical and functional interaction between Gab1 and PTP1B.
Indeed, we demonstrate a physical and functional interaction between HMGA1 and Bcl-2 proteins.
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The amygdala plays a role in REM sleep modulation [37], and functional interactions between the amygdala and the cortex was demonstrated by PET data during REM sleep [38].
In this analysis, we report an in-house model to describe the complex fundamental and functional interactions between various internal physico-chemical phenomena of a SOEC.
Therefore, integrative examination of MNase footprints reveals insights into nucleosome dynamics and functional interactions between chromatin structure and key gene-regulatory factors.
Moreover, physical and functional interactions between BLOC-1 components and AP-3 components were reported recently [64], [65].
We also identify physical and functional interactions between Ccr4-Not subunits and multiple NPC components, and implicate these interactions in mRNA export.
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