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The PSD includes 20 items encompassing symptom severity, bother, and functional impacts of itch, stinging, burning, cracking, pain, scaling, and skin color change.
Visualisation of these interactions provides insights into the nature of molecular recognition events and has practical uses in guiding drug design and understanding the structural and functional impacts of mutations.
We look forward to further studies that attempt to unravel the phylogenetic association between the composition and concentration of eggshell pigments and the evolutionary drivers and functional impacts of variability in eggshell colour.
The downside of this result was that for those cases, we no longer have evidence as to which flavor of disorder is predicted; this makes interpretations about the structural and functional impacts of the region more challenging.
We suggest that future studies investigating the phylogenetic association between the composition and concentration of eggshell pigments, and between the evolutionary drivers and functional impacts of eggshell colour variability will be most rewarding.
Beyond the structural and functional impacts of the changes we have measured, the sites of altered PTMs may be used to identify enzymes responsible for their modulation, which could be used as prospective drug targets for highly specific AD therapies.
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In silico analysis of the structural and functional impact of the studied variant was also executed.
To develop measures of the day-to-day symptomatic and functional impact of recurrent genital herpes (RGH) outbreaks.
In both cases, incidence and functional impact of these BAEs have not been determined and are currently not included in clinical guidelines.
We review the structural and functional impact of active-site mutations with respect to enzyme activity and antifolate resistance of DHFRs from mammals, protozoa and bacteria.
Limited research has examined the clinical and functional impact of concurrent posttraumatic stress disorder (PTSD) in people with borderline personality disorder (BPD).
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