The phrase "and functional hallmarks of" is correct and usable in written English.
It can be used when discussing specific characteristics or features that are indicative of a particular function or role, often in scientific or technical contexts.
Example: "The study identified several key biomarkers and functional hallmarks of cancer progression."
Alternatives: "and functional characteristics of" or "and operational features of".
We report that chronic hypoxia in chick embryos resulted in LV dilatation and several other structural and functional hallmarks of cardiomyopathy.
The developmental pathways of DCs are summarized in Figure 1. Figure 2 illustrates the immunophenotypic and functional hallmarks of blood DCs.
These include homology to known metazoan prohormones (e.g., NPY, AKH, 7B2 [ 70, 71]), a confirmed expression in Platynereis neurons (e.g., FVMa, SPY [ 28]), MS evidence (e.g., NGEW, GYa), conservation across lophotrochozoans or annelids (e.g., CCWa, QSGa) and other structural and functional hallmarks of a prohormone, such as a repetitive structure or peptide modifications (e.g., SPRa, QRIa).
A large body of literatures indicated that increased cell migration and invasion are functional hallmarks of EMT and are also important steps during the cascade of tumour metastasis [ 38].
However, it is noteworthy that the deep fascia of various species and regions might have diverse morphological and functional hallmarks.
These pathways have many common characteristics; for example, AMPK can regulate the function of all these pathways, and many of them target the regulation of autophagy and oxidative stress, functional hallmarks of the aging process (Salminen & Kaarniranta, 2012).
Furthermore, knockdown of TAZ in PC9/GR suppressed cell migration and invasion, which were considered functional hallmarks of EMT.
Next, we examined migratory and invasive potential, which are considered functional hallmarks of EMT.
DOI: http://dx.doi.org/10.7554/eLife.07051.010 In P2b::CreBAC1;Atoh1 lox/lox mutants, we looked for cells displaying the functional hallmarks of the embryonic RTN: rhythmic activity, acid-sensitivity and entrainment of the RRG (Thoby-Brisson et al., 2009).
Functional hallmarks of hSlo3 as seen in sperm can be recapitulated in CHO cells expressing recombinant hSlo3 and the auxiliary subunit LRRC52.
Recently, a population of human peripheral blood B cells with a CD20+IgD+CD27+CD43+CD70− phenotype has been shown to exhibit the functional hallmarks of the mouse B1 cells [ 28], although its actual significance and magnitude remain to be further explored.
