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NDs are characterised by progressive neuropsychiatric dysfunction and the loss of structure and function of specific neuronal circuitry that in turn result in behavioural symptoms.
We tested the hypothesis that glucocorticoid treatment and food restriction have a selective effect on synthesis and function of specific muscle protein units, particularly in the mitochondria.
Associated with stronger depth of sequencing (e.g. 454 [39]), this approach will probably help to achieve a nearly exhaustive view of protist diversity and to better appreciate the contribution and function of specific organisms in the microbial food web.
These expression domains imply that, in addition to a possible involvement in patterning, these factors may also play a role in the differentiation and function of specific neuron classes.
We used three types of mutants: (1) cilium structure mutants which have defects in the sensory endings of ciliated sensory neurons, (2) sensory transduction mutants which lack components necessary for signal transduction, and (3) neuron specification mutants which lack transcription factors that are necessary for the correct development and function of specific neurons.
However, little is known about expression and function of specific HDAC isoforms in human tumours including prostate cancer.
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Intensive studies will be necessary to investigate the structures and functions of specific peptides of the venom in the future.
The brain is of bewildering complexity and numerous genes and signaling molecules have been described that affect the architecture and functioning of specific neuronal circuits.
The mammalian genome contains on the order of a million enhancer-like regions that are required to establish the identities and functions of specific cell types.
Therefore, by mimicking the structure and property of the natural tissues, synthetic nanopolymers and nanocomposites are very likely to enhance or even regulate the responses and functions of specific cells or tissues.
Glucocorticoids levels are high in catabolic conditions but it is unclear how much of the catabolic effects are due to negative energy balance versus glucocorticoids and whether there are distinct effects on metabolism and functions of specific muscle proteins.
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CEO of Professional Science Editing for Scientists @ prosciediting.com