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Our data describe a novel immunoregulatory property of sHLA-G molecules, based on the inhibition of chemokine-driven migration of different T cell populations together with downregulation of the expression and function of selected chemokine receptors on these cells.
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Further, we explore disease subtype specificity and functions of selected expressed pseudogenes.
In this model system, we carried out CS-SELEX by establishing a stable cell line that ectopically expressed the HCV E2 glycoprotein on the cell surface and examined the binding affinities and functions of selected ssDNA aptamers.
The expression profiles and biological function of selected miRNAs and mRNAs were analysed in more detail.
Virus-induced gene silencing is being used to screen candidate genes for their involvement in MIA biosynthesis, and the function of selected genes can be identified by the expression and assay of recombinant proteins in bacterial or yeast systems.
To establish expression profile and infer function of selected genes, we consulted seven somatic transcriptomes from six organs (gill, outer and pallial mantle, adductor muscle, digestive gland, labial palp, and hemocytes) and transcriptomes from 38 developmental stages that were obtained in our previous study (Zhang et al. 2012).
Table 2 summarizes the chromosomal position and function of the selected SNPs.
Working from the list of differentially expressed genes, we identified genes expressed in tissues of interest to us (neoblasts, blastema, and CNS) and then examined the function of selected genes by RNAi.
Predictions for the conversion of n-butane and yield of MAN are presented as a function of selected operating variables, and the impact of the variable model parameters on the predictions is briefly assessed.
A comprehensive parametric study is accomplished and analytical expressions to estimate stress concentration factors for spherical, longitudinal and transverse plain dents as a function of selected geometric parameters are developed.
The overall exothermicity of the preignition n-heptane oxidation chemistry and the fuel consumption rates are examined as a function of selected independent parameters, namely temperature, fuel concentration, and residence time; their influence on cool flame reactivity is thoroughly studied.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com