A patient-derived iPSC line containing the CEP290-R1746Q variant (#725) exhibits altered cilia morphology and function as well as diminished response to Shh-N stimulation.
Includes a review of cell structure and function, as well as the mechanisms by which the endocrine and nervous systems integrate cellular metabolism.
The significance of this crosstalk is further demonstrated by targeting macrophage polarization and function, as well as altering disease course in established experimental disease.
In order to study brain structure and development changes, researchers measure brain structure and function as well as behavioral, motor, and cognitive abilities over time.
Genome duplication is responsible for shaping the architecture and function as well as the evolution of many higher plant genomes, and gives rise to new or modified gene functions23,24,25.
Elucidation of their structure and function as well as of their regulation began 30 40 years ago and the advance has markedly increased during the last 15 years.
Multimodal imaging is an important part of the study of placenta structure and function, as well as embryonic development, particularly in transgenic mice.
Chang's research focuses on understanding how small molecules attached to the DNA affect gene expression and coordinate cell fate and function, as well as on the role played by long noncoding RNAs and other RNA structures in biological regulation.
His research focuses on understanding how epigenetic tags on DNA affect gene expression and coordinate cell fate and function, as well as on the role played by long noncoding RNAs and other RNA structures in biological regulation.
In particular, we will focus on the molecular mechanisms of these interactions and their role in brain development and function as well as their potential contributions to specific neurological disorders, including autism.
It takes great thought and artistry to produce a shape as perfect as the incandescent bulb, and it will take some while yet to perfect the sustainable lightbulb's form and function, as well as the colour of the light it emits.
