By use of transfection-complementation experiments in cultured cells, with or without DMPK deficiency, we analyze hDMPK A's role in determining mitochondrial fate and function and the functional integrity of the cell.
Metal ions play important roles in protein and RNA structure and function and the construction of ligands frequently focuses on the exploitation of functionality designed to engage a metal.
If one begins with the assertion that healthy, native tissues represent a design optimum, the task of systems biology is to identify the "control knobs" that govern tissue structure and function, and the specific "settings" of these knobs that yield an optimally functional (i.e., healthy) tissue.
The more you have political instability, the harder it is for institutions to consolidate and function, and the more likely the electorate is to lose patience".
Their complex arrangement and function, and the distribution of fine and delicate nerves that supply them, can only be understood by dissection.
Novel species assemblages can also substantially alter ecosystem structure and function and the distribution of ecosystem services.
This article examines the physical principles that underlie transducer design and function, and the sources of error and inaccuracy.
The variables for postoperative outcomes were the WOMAC scores (pain and function) and the level of patient satisfaction.
Scientists have long been fascinated with the associations between form and function and the presumption that one begets the other.
The chapter discusses the major aspects of basidiomycete mycelial structure and function and the effect of the abiotic environment on function.
Immunohistochemistry and quantitative reverse-transcriptase polymerase chain reaction were used to assess the maintenance of cellular phenotype and function, and the formation of extracellular matrix.
