Sentence examples for and eventually the development from inspiring English sources

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His determination to bring the secret to north America led to a bizarre 50-mile race between the tribespeople and a motley group of US "ultra runners" in the Copper Canyons and eventually the development of a $2bn industry based on barefoot-style shoes.

The crucial idea was that a large amount of well dispersed investment should be made in the economy, so that the market size expands and leads to higher productivity levels, increasing returns to scale and eventually the development of the country in question.

Recent work on the molecular processes that underpin the pathophysiology of COPD has also implicated inappropriate activation of the coagulation cascade and in particular thrombin and plasmin as potential factors that may promote pulmonary inflammation, airway remodelling and eventually the development of emphysema via protease activated receptors [11].

Angiogenesis consists of a series of endothelial cell activities including response to pro-angiogenic growth factor signals, stimulation of cell proliferation, degradation of the vascular basement membrane, endothelial cell sprouting, migration and invasion of activated cells, formation of lumenized endothelial stacks and eventually, the development of anastomoses and capillary networks [25].

Anti-TNF-alpha therapies may inhibit these apoptotic processes and promote persistence of inflammatory cells in the lung parenchyma and eventually the development of ILD [ 92].

Conditional deletion of the Brca1 gene from the mouse mammary gland resulted in developmental abnormalities and, eventually, the development of p53-null tumours.

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The original obstacles of immunogenicity of murine mAbs in humans was overcome by the revolution in molecular biology in the 1980s, which enabled humanization of murine antibodies and, eventually, the successful development of fully humanized antibodies.

Indeed, since miRNAs expression is deeply related to cellular behavior and, eventually, the correct development and function of body tissues, changes in miRNAs expression profiles are being extensively studied in human diseases such as cancer, osteoporosis, cardiac illness and heart failure [22] [25].

The shift of balance of these three pathways into one or the other direction will tilt the hormonal balance through the steroidogenic pathway and eventually push the development toward one of the two gonad types.

Together, levels and breadths of gene expression shape the diversity of organismal transcriptomes and eventually facilitate the development and the maintenance of complex biological systems.

In the yda mutant, it was shown that the zygote could not divide properly, leading to inappropriate cell divisions of the suspensor and, eventually, to the development of an embryo without the root primordium [ 20].

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