The phrase "and eventually activation of" is correct and usable in written English.
It can be used in contexts where you are describing a process that leads to the activation of something over time.
Example: "The treatment involves several stages, including initial assessment, therapy sessions, and eventually activation of the healing process."
Alternatives: "and ultimately triggering of" or "and finally initiation of".
In summary, these results strongly suggest that during early mitosis GRASP65 is first phosphorylated on residue S277, followed by modification of the S376 residue, and eventually activation of T220/T224.
Staying in a "waiting mode", they are steadily exposed to internal and external mutagens what results in a gradual erosion of the system of checks-and-balances (protooncogenes and suppressor genes) and, eventually, activation of the cryptic "cancer differentiation".
We believe that due to chromosome end fusions, there are chromosome breakage-fusion-bridge events, leading to genomic instability, rearrangements of chromosomes and eventually activation or upregulation of telomerase.
This transduction involves activation of Type I and Type II IFN receptors, receptor-associated JAK/TYK (tyrosine kinase) kinases and eventually activation and nuclear translocation of STAT1.
For instance, the phosphorylated tyrosine pY1214 of VEGFR2 allows recruitment of NCK and FYN as well as eventually activation of p38 MAPK pathway, which is important for EC migration (Lamalice et al., 2006), while VEGF/VEGFR2-induced activation of the RAS/RAF/ERK/MAPK pathway is responsible for EC proliferation (Meadows et al., 2001; Zachary, 2001).
Eventually, activation of caspase-3 results in DNA fragmentation and apoptosis [ 55].
Eventually, activation of CaMKII can lead to physiological changes in the strength of synaptic connections (13, 14) and modulate the force/contraction relationship in cardiac tissues, among many other functions (15– 15).
Ach binding to M5Rs leads to the activation of G proteins of the Gq family which in turns triggers increases in intracellular calcium and inositol 1,4,5-triphosphate levels [13] [16] and eventually the activation of endothelial NO synthase (eNOS) and the production of NO [12].
Such external trace amounts of nitrate may occur as contaminants of media components which might accumulate over time inside NR-mutant cells by nitrate transporter activity, and eventually lead to activation of NirA.
These cytokines are released closely to the target cells and modulate the expression of complex gene networks in β cells, leading to the release of chemokines and eventually to the activation of the intrinsic pathway of cell death in β cells (Eizirik et al., 2009; Gurzov and Eizirik, 2011).
Thioredoxin-1 (Trx1), a conserved antioxidant protein that is well known for its disulfide reductase activity, can physically associate with the SARAH domain of Mst1 in intact cells and inhibit the homodimerization and autophosphorylation of Mst1, thereby prevents Mst1 activation; whereas H2O2 abolishes this interaction and eventually causes the activation of Mst1.
