The phrase "and essential player in" is correct and usable in written English.
It can be used to describe someone or something that plays a crucial role in a particular context or situation.
Example: "The company has become an essential player in the renewable energy sector, driving innovation and sustainability."
Alternatives: "a key contributor to" or "a vital participant in".
This number is significantly greater than the random case (P<2.0×10−4, randomization test; Figure 5A), indicating that this module seems to be the critical and essential player in tumorigenesis.
Of note, EF1-α, a well-known and essential player in protein translation and an important polysomal component with RNA-binding properties, was independently identified in a yeast two-hybrid screen with MID1 as bait and showed perfect co-localisation with MID1 at the microtubules.
Other directions to extend the model are of course to include other feedback loops and essential players in p53 regulation, such as Wip1 [ 20] and MdmX [ 10], and to model the connection between p53 levels and physiological behaviour more accurately as has been done for cell cycle arrest in ref. [ 44].
Interferon alpha (IFNα) is rapidly upregulated in response to viral infections [7], [8], [9], and is an essential player in antiviral immune responses: it induces the expression of cellular genes that interfere with viral replication, activates NK cell function, and promotes maturation of antigen presenting cells [10], [11], [12], [13], [14].
With the vast amount of work still to be done, microarray technology will have an increasingly important role in the post-genomic era and will most certainly be an essential player in the post-genomic era.
Intriguingly, a recent study found that α-catenin co-IPs with motif B of hAPC1, and suggests α-catenin is an essential player in destruction complex function (Choi et al., 2013).
Kerry told a press conference that the new Administration considered Syria "an essential player in bringing peace and stability to the region".
Stevens was successful from the outset and for the next five years an essential player in what must be seen as a last great flowering of the British repertory movement, as he created a nexus of vibrant new northern houses – the Newcastle Playhouse included – which made a heavy workload even for one so committed to regional theatre.
The HGF/MET pathway is thus an essential player in normal development and wound healing [ 56, 57].
Not surprisingly, MLCK is an essential player in both migration and invasion in response to all of the stimuli tested here, as it is central to the control of myosin II phosphorylation and subsequent activation.
SMG-1 is critical component of the mRNA surveillance complex known to be involved in the non-sense mediated mRNA decay., Furthermore, R2TP-Hsp90 complex is essential player in the stability and assembly of PIKKs.
